P-Selectin also called Platelet Alpha-Granule Membrane Protein， CD62， and Granulocyte Membrane Protein GRMP belongs to a family of divalent cation-dependent carbohydrate-binding glycoproteins or adhesion molecules. Pselectin is expressed transiently on the surface of activated platelets and endothelial cells. P-Selectin is a 140 kDa protein which is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Secreted P-selectin is thought to play a key role in the adhesion of platelets to monocytes and neutrophils during an inflammatory response. P-Selectin is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Levels of P-Selectin may be elevated in a number of pathological conditions.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered liquid formulation. P-Selectin is supplied in 50% Glycerol.
保存建议
Store at 4℃ if entire vial will be used within 1-2 weeks.
Store， frozen at -20℃ for longer periods of time.
Avoid multiple freeze-thaw cycles.
