Ang K1-3 is a proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. More active relative to kringles 1-4. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth.
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来源宿主
大肠杆菌中重组表达
溶解建议
Sterile Filtered White lyophilized （freeze-dried） powder. Lyophilized from a 0.2um filtered concentrated （1.0mg/ml） solution in 20mM NaAc， pH5.5， 4% mannitol. We recommend to briefly centrifuge the vial prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
保存建议
The lyophilized Angiostatin K1-3 is stable for several weeks at 2-8℃， but should be kept at -20℃ for long term storage， preferably desiccated. Upon reconstitution， the preparation is stable for up to one week at 2-8℃. For maximal stability， apportion the reconstituted preparation into working aliquots and store at -20℃ to -70℃.
Avoid repeated freeze/thaw cycles.
