SIRT6 is part of the sirtuin family of proteins （Class IV）， homologs to the yeast Sir2 protein. SIRT6 is characterized by a sirtuin core domain. Yeast sirtuin proteins are recognized by their ability to regulate epigenetic gene silencing and suppress recombination of rDNA. SIRT6， a chromatin-associated protein is involved in DNA repair. Human Sirtuins function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
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大肠杆菌中重组表达
溶解建议
Sterile Filtered colorless solution. The SIRT6 protein solution contains 20mM Tris-HCl pH-8 & 10% glycerol.
保存建议
SIRT6 although stable 4℃ for 4 weeks， should be stored desiccated below -18℃.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.
