Actin-related protein 2/3 complex subunit 3 （ARPC3） which Belongs to the ARPC3 family is one of 7 subunits of the human Arp2/3 protein complex. The Arp2/3 complex is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor （NPF） mediates the formation of branched actin networks. ARPC3 which is localized to the cytoplasm and cytoskeleton， interacts with p20-ARC and takes part in the structural integrity of the protein complex.
