Cadherin 11 （CDH11） belongs to the cadherin superfamily （integral membrane proteins） which mediate calcium-dependent cell-cell adhesion. CDH11 is defined based on lacking a HAV cell adhesion recognition sequence specific to type I cadherins. CDH11 protein’s expression in osteoblastic cell lines， and its upregulation during differentiation， suggests a specific function in bone development and maintenance. CDH11 contributes to the sorting of heterogeneous cell types.
