LIN7B （VELI2）， is a member of the Velis family. Velis family contains minor synaptic proteins which interact with other proteins at the post-synaptic density （PSD） of neuronal synapses. Velis which contain the PDZ motif， participate in recruiting cell adhesion molecules， receptors， and channels. Lin7B protein is ubiquitously expressed with a high expression in the brain， liver， and testis. Lin7B localizes at the synaptic junctions in neurons， bind to CASK， which is a neurexin-binding protein highly concentrated in synapses， and Mint1， a binding partner with a vesicle trafficking protein.
