MRPL28 is found in a variety of normal tissues such as spleen， testis， thymus， liver， kidney， brain， adrenal， lung and retinal tissue. 39S ribosomal protein L28， mitochondrial （MRPL28）， is a part of the ribosomal protein L28P family. Mammalian mitochondrial ribosomal proteins encoded by nuclear genes and helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes （mitoribosomes） consist of a small 28S subunit and a large 39S subunit. MRPL28 is an important therapeutic reagent for HLA-A24 （A24） patients since this antigen is distinguished by tumor-infiltrating lymphocyte （TIL） 1290， which targets the A24 serotype.
