Steroid receptor RNA activator 1 （SRA1） occurs as both an RNA transcript and as constantly expressed proteins. In addition， SRA1 mediates transcriptional coactivation of steroid receptors ligand-dependently via the steroid-binding domain （AF-2）. SRA1 augments cellular proliferation and differentiation and stimulates apoptosis in vivo. SRA1 has a role in tumorigenesis. SRA1 participates in some activities such as: metabolism， adipogenesis and chromatin organization.
