60S ribosomal protein L8 （RPL8） is a member of the ribosomal protein L2P family. Ribosomes consist of a small 40S subunit and a large 60S subunit. RPL8 is found in the cytoplasm and exists as a component of the 60S subunit where it is assumed to have role in aminoacyl-tRNA binding， specifically at the ribosomal subunit interface. In rats， the RPL8 protein connects with the 5.8S rRNA， and possibly participates in the binding of aminoacyl-tRNA， and is a component of the elongation factor 2-binding site at the ribosomal subunit interface.
