Prefoldin subunit 2 （PFDN2） belongs to the prefoldin beta subunit family. The PFDN2 protein is one of 6 subunits of prefoldin， which is a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides， thus allowing them to fold correctly. PFDN2 binds specifically to cytosolic chaperonin （c-CPN） and transfers target proteins to it. PFDN2 also binds to a nascent polypeptide chain and promotes folding in an setting in which there are many competing pathways for nonnative proteins.
