The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
应用类型
WB
免疫原
Synthetic peptide corresponding to residues near the N terminal of human aryl-hydrocarbon receptor repressor
