zinc finger C3HC-type containing 1(ZC3HC1) Homo sapiens This gene encodes an F-box-containing protein that is a component of an SCF-type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2/M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin-dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis. [provided by RefSeq, Aug 2013],
应用类型
WB,ICC
免疫原
The antiserum was produced against synthesized peptide derived from human NIPA around the phosphorylation site of Ser354. AA range:320-369
