Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death.
应用类型
WB,IHC
免疫原
Synthetic peptide corresponding to residues near the C terminal of human poly (ADP-ribose) polymerase family, member 8