The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene.
应用类型
WB,IHC
免疫原
Synthetic peptide corresponding to a region derived from internal residues of human Transient receptor potential cation channel, subfamily C, member 3
