The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
应用类型
WB,IHC
免疫原
Fusion protein corresponding to residues near the C terminal of human Suppressor of fused homolog (Drosophila)
