Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.Zannis V.I., J. Biol. Chem. 259:5495-5499(1984).McLean J.W., J. Biol. Chem. 259:6498-6504(1984).Paik Y.-K., Proc. Natl. Acad. Sci. U.S.A. 82:3445-3449(1985).
应用类型
WB
免疫原
Synthesized peptide derived from C-terminal of human APOE.