Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.Sakano S., Oncogene 9:1155-1161(1994).Bennett B.D., J. Biol. Chem. 269:1068-1074(1994).Avraham S., J. Biol. Chem. 270:1833-1842(1995).
应用类型
WB
免疫原
Synthesized peptide derived from Internal of human MATK.
