Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.Oka M., Submitted (DEC-2003).Sugano S., Nat. Genet. 36:40-45(2004).Ohara O., DNA Res. 7:347-355(2000).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human SNIP.
