Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity.Fernandez-Silva P., EMBO J. 16:1066-1079(1997).Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.Hillier L.W., Nature 424:157-164(2003).
应用类型
WB,IHC
免疫原
Synthesized peptide derived from internal of human MTERF.