Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.Ota T., Nat. Genet. 36:40-45(2004).Gregory S.G., Nature 441:315-321(2006).Bechtel S., BMC Genomics 8:399-399(2007).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human TOR1AIP1.
