Mediates the Na+-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids By similarity. Selectively inhibited by the grapefruit juice component naringin.Kullak-Ublick G.-A., Gastroenterology 109:1274-1282(1995).Koenig J., J. Biol. Chem. 275:23161-23168(2000).Lee W., J. Biol. Chem. 280:9610-9617(2005).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human SLCO1A2.