Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier By similarity.Eubanks J., NeuroReport 8:2775-2779(1997).Bolino A., Eur. J. Hum. Genet. 6:629-634(1998).Cruz J.S., Science 284:711-711(1999).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human SCN2B.
