Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.George A.L. Jr., Proc. Natl. Acad. Sci. U.S.A. 89:4893-4897(1992).
应用类型
ICC
免疫原
Synthesized peptide derived from internal of human SCN7A.