Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha By similarity.Chatterjee T.K., Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.Seki N., J. Hum. Genet. 43:202-205(1998).Cismowski M.J., Nat. Biotechnol. 17:878-883(1999).
应用类型
WB,IHC
免疫原
Synthesized peptide derived from internal of human RGS5.