Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.Fujimoto-Nishiyama A., Gene 195:267-275(1997).Date S., Int. J. Mol. Med. 13:637-642(2004).The MGC Project Team; Genome Res. 14:2121-2127(2004).
应用类型
IHC
免疫原
Synthesized peptide derived from internal of human RREB1.
