Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation.Nagase T., DNA Res. 3:321-329(1996).Scherer S.W., Science 300:767-772(2003).Ichiba T., FEBS Lett. 457:85-89(1999)
应用类型
WB
免疫原
Synthesized peptide derived from internal of human RAPGEF5.
