Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.Tewari D.S., Biochim. Biophys. Acta 1209:293-295(1994).Hideyama T., Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.Yang D., Biochem. Mol. Biol. Int. 38:957-964(1996).
应用类型
IHC
免疫原
Synthesized peptide derived from N-terminal of human OAZ1.
