Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.Poulat F., J. Biol. Chem. 272:7167-7172(1997) [PubMed: 9054412].Reczek D.,J. Cell Biol. 139:169-179(1997) [PubMed: 9314537].Yun C.H.C., Proc. Natl. Acad. Sci. U.S.A. 94:3010-3015(1997) [PubMed: 9096337].
应用类型
WB
免疫原
Synthesized peptide derived from internal of human SLC9A3R2.
