Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. May be involved in the remodeling of the actin cytoskeleton. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activating protein on Rho.Wirth J.A., J. Cell Sci. 109:653-661(1996).Grewal P.K., Gene 240:389-398(1999).Post P.L., J. Cell Sci. 111:941-950(1998).
应用类型
WB
免疫原
Synthesized peptide derived from N-terminal of human MYO9B.