Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase.Thiel S., Nature 386:506-510(1997).Takahashi M., Int. Immunol. 11:859-863(1999).Stover C.M., J. Immunol. 162:3481-3490(1999).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human MASP2.
