Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.Trowsdale J., EMBO J. 4:2231-2237(1985).Jonsson A.-K., Immunogenetics 29:411-413(1989).Young J.A., Immunogenetics 31:386-388(1990).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human HLA-DOA.
