Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons.Kageyama R., Cell 59:815-825(1989).Hillier L.W., Nature 434:724-731(2005).The MGC Project Team; Genome Res. 14:2121-2127(2004).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human GCF.
