Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.Yao R., Proc. Natl. Acad. Sci. U.S.A. 93:10134-10138(1996).Yin D., Gene 238:463-470(1999).Basrur V., J. Proteome Res. 2:69-79(2003).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human GGH.
