Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol By similarity.Tannin G.M., J. Biol. Chem. 266:16653-16658(1991).Draper N., J. Clin. Endocrinol. Metab. 87:4984-4990(2002).Ota T., Nat. Genet. 36:40-45(2004) .
应用类型
WB,IHC
免疫原
Synthesized peptide derived from N-terminal of human HSD11B1.
