Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.Villard L., Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.Oh S.J., Biochim. Biophys. Acta 1493:219-224(2000).Rentsch A., Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
应用类型
WB
免疫原
Synthesized peptide derived from internal of human KIF4A.