Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.Pittler S.J., J. Biol. Chem. 267:6257-6262(1992).Dhallan R.S., J. Neurosci. 12:3248-3256(1992).Ota T., Nat. Genet. 36:40-45(2004).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human CNGA1.
