Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.Joberty G., Mol. Cell. Biol. 19:6585-6597(1999).Hirsch D.S., J. Biol. Chem. 276:875-883(2001).Wiemann S., Genome Res. 11:422-435(2001).
应用类型
WB
免疫原
Synthesized peptide derived from N-terminal of human CDC42EP3.
