The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y.Franco B., Cell 81:15-25(1995).Urbitsch P., DNA Cell Biol. 19:765-773(2000).
应用类型
IHC,ICC
免疫原
Synthesized peptide derived from internal of human ARSD.