Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.Bratt A., Gene 298:69-77(2002).Bratt A., Gene 310:231-231(2003).Yu L.-R., J. Proteome Res. 6:4150-4162(2007).
应用类型
IHC
免疫原
Synthesized peptide derived from internal of human AMOTL1.
