Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.Hadano S., Nat. Genet. 29:166-173(2001).Tao X., Neuron 33:383-395(2002).Hillier L.W., Nature 434:724-731(2005)
应用类型
WB,IHC
免疫原
Synthesized peptide derived from internal of human ALS2CR8.