After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.Beeson D.M.W., Nucleic Acids Res. 17:4391-4391(1989).Gomez C.M., Ann. Neurol. 39:712-723(1996).Engel A.G., Hum. Mol. Genet. 5:1217-1227(1996).
应用类型
WB
免疫原
Synthesized peptide derived from N-terminal of human CHRNB1.
