Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity.Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).Dunham I., Nature 402:489-495(1999).
应用类型
IHC
免疫原
Synthesized peptide derived from internal of human RPS19BP1.