SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A3 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).Yamazaki K., J. Biol. Chem. 277:26444-26451(2002).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human ELOA3.
