Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.Miles J.S., ic Acids Res. 17:2907-2917(1989).Yamano S., Biochemistry 29:1322-1329(1990).Saito S., J. Hum. Genet. 48:249-270(2003).
应用类型
WB
免疫原
Synthesized peptide derived from N-terminal of human Cytochrome P450 2A6.
