Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.Prescott J.E.,J. Biol. Chem. 276:48276-48284(2001).Ota T.,Nat. Genet. 36:40-45(2004).Hillier L.W., Nature 434:724-731(2005).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human CDCA7.
