Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.Zupan L.A., J. Biol. Chem. 267:8707-8710(1992).Seluja G.A., Biochim. Biophys. Acta 1395:281-287(1998).Gevaert K., Nat. Biotechnol. 21:566-569(2003).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human 14-3-3 ζ.