Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments.Lee K., Cancer Res. 60:3631-3637(2000).Grimwood J., Nature 428:529-535(2004).Lim S., . Biol. Chem. 277:25040-25046(2002).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human DYR1B.
