Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes.Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).Boopathi E., J. Biol. Chem. 279:35242-35254(2004).Beausoleil S.A., Nat. Biotechnol. 24:1285-1292(2006).
应用类型
WB,IHC
免疫原
Synthesized peptide derived from internal of human ZNF148.
