The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins By similarity. UniProtKB Q9ESN9Hattori A., DNA Res. 7:357-366(2000).Martin J., Nature 432:988-994(2004).Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).
应用类型
WB,ICC
免疫原
Synthesized peptide derived from internal of human JIP3.
