Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade.Kitching R., Biochim. Biophys. Acta 1625:116-121(2003).Amid C., Cytogenet. Cell Genet. 93:284-290(2001).Ota T., Nat. Genet. 36:40-45(2004).
应用类型
WB,IHC
免疫原
Synthesized peptide derived from internal of human BCA3.